Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Aminobenzamide

  • CAS No. 3544-24-9

  • Cat. No. CS-0157
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD00007989

*For research and further manufacturing use only, not for direct human use.

3-Aminobenzamide|CS-0157

Structure of 3544-24-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 3544-24-9
  • Cat. No. CS-0157
  • Purity ≥97%
  • MDL No. MFCD00007989
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O
  • Molecular Weight None
  • Synonym(s) PARP-IN-1
  • SMILES O=C(C1=CC=CC(N)=C1)N

Description

cataCXium A Pd G3 is a Buchwald third-generation precatalyst that can be used in:Direct ortho-arylation of pyridinecarboxylic acids.Catalyzing SuzukiMiyaura cross-coupling in the synthesis of 1-heteroaryl-3-azabicyclo[3.1.0]hexanes.Palladium-catalyzed carbonylative carboperfluoroalkylation of alkynes.SuzukiMiyaura coupling reaction of geminal bis(boryl)cyclopropanes in the synthesis of various gem-disubstituted cyclopropanes.Boroperfluoroalkylation of terminal alkynes.Copper-free Sonogashira coupling reaction of aromatic halides with alkynes to form C-C bond.Suzuki cross-coupling between organotrifluoroborate and aryl halides.For small scale and high throughput uses, product is also available as ChemBeads (928305)

Application

PARP Inhibitor I, 3-ABA (CAS 3544-24-9) inhibits poly-(ADP-ribose) polymerase activity by targeting the catalytic domain of PARP enzymes, disrupting DNA repair mechanisms in cancer cells. This interference enhances cytotoxicity. Researchers leverage this to sensitize tumor cells to radiation and chemotherapy.

Synthesis

  • Route1

    References

    • Rahaim Jr., Ronald J.; Maleczka Jr., Robert E. Synthesis, 2006 , # 19 p. 3316 - 3340
  • Route2
    • null|null
      2237-30-1
    • ~99%
    • In-stock
      3-Aminobenzamide|CS-0157
      3544-24-9

    References

    • Brinchi, Lucia; Chiavini, Lisa; Goracci, Laura; Di Profio, Pietro; Germani, Raimondo Letters in Organic Chemistry, 2009 , vol. 6, # 2 p. 175 - 179
  • Route3
    • 3-Aminobenzaldehyde|CS-0448288
      1709-44-0
    • ~91%
    • In-stock
      3-Aminobenzamide|CS-0157
      3544-24-9

    References

    • Sharghi, Hashem; Sarvari, Mona Hosseini Tetrahedron, 2002 , vol. 58, # 52 p. 10323 - 10328

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   69.11
  • LogP   0.3677
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Aminobenzamide sigma3-Aminobenzamide manufacturer3-Aminobenzamide price3-Aminobenzamide structure3-Aminobenzamide SDSbuy 3-Aminobenzamide3-Aminobenzamide supplier3-Aminobenzamide uses3-Aminobenzamide molecular weightprice of 3-Aminobenzamide3-Aminobenzamide chemical name formula of 3-Aminobenzamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label