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Structure of 3544-24-9
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cataCXium A Pd G3 is a Buchwald third-generation precatalyst that can be used in:Direct ortho-arylation of pyridinecarboxylic acids.Catalyzing SuzukiMiyaura cross-coupling in the synthesis of 1-heteroaryl-3-azabicyclo[3.1.0]hexanes.Palladium-catalyzed carbonylative carboperfluoroalkylation of alkynes.SuzukiMiyaura coupling reaction of geminal bis(boryl)cyclopropanes in the synthesis of various gem-disubstituted cyclopropanes.Boroperfluoroalkylation of terminal alkynes.Copper-free Sonogashira coupling reaction of aromatic halides with alkynes to form C-C bond.Suzuki cross-coupling between organotrifluoroborate and aryl halides.For small scale and high throughput uses, product is also available as ChemBeads (928305)
PARP Inhibitor I, 3-ABA (CAS 3544-24-9) inhibits poly-(ADP-ribose) polymerase activity by targeting the catalytic domain of PARP enzymes, disrupting DNA repair mechanisms in cancer cells. This interference enhances cytotoxicity. Researchers leverage this to sensitize tumor cells to radiation and chemotherapy.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: