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Structure of 26059-40-5
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2-(2-Iodophenyl)ethan-1-ol features a benzene ring bearing both iodine and hydroxymethyl substituents in ortho orientation, enabling direct functionalization in cross-coupling reactions. The pendant alcohol group provides a handle for derivatization, while the iodophenyl moiety offers high reactivity in palladium-catalyzed transformations. This compound serves as a versatile intermediate in synthetic routes to bioactive molecules and advanced materials.
2-(2-Iodophenyl)ethan-1-ol serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to biaryl architectures. Its iodide functionality exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the pendant primary alcohol offers straightforward derivatization options. The compound demonstrates excellent bench stability and is readily purified by flash chromatography, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: