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Structure of 261762-46-3
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(3-Chloro-2,6-difluorophenyl)methanamine is a bench-stable arylamine featuring electron-withdrawing chlorine and fluorine substituents that enhance reactivity in coupling processes. This trifluorinated benzylamine integrates readily into pharmaceutical intermediates, offering improved metabolic stability and solubility in polar reaction media.
(3-Chloro-2,6-difluorophenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds prevalent in agrochemicals and pharmaceuticals. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient incorporation into complex molecules. The ortho-fluoro substituents enhance metabolic stability, while the primary amine functions as a key handle for diversification via acylation, alkylation, or reductive amination.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: