2,2,6,6-Tetramethylpiperidin-4-yl benzoate

Name: 2,2,6,6-Tetramethylpiperidin-4-yl benzoate
Brand: ChemScene
Availability: InStock
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CAS No. 26275-88-7
Cat. No. CS-0654108
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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*For research and further manufacturing use only, not for direct human use.

2,2,6,6-Tetramethylpiperidin-4-yl benzoate|CS-0654108

Structure of 26275-88-7

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Description

2,2,6,6-Tetramethylpiperidin-4-yl benzoate features a sterically hindered piperidine core that enhances stability and solubility in organic media. This ester derivative serves as a robust protecting group for alcohols and amines, enabling efficient coupling reactions under mild conditions. Its bench-stable nature simplifies handling in synthetic workflows.

Application

2,2,6,6-Tetramethylpiperidin-4-yl benzoate serves as a robust and bench-stable benzoyl protecting group for alcohols and amines, enabling selective derivatization under mild conditions. Its steric bulk enhances stability against hydrolysis and nucleophilic attack, while the piperidine core facilitates efficient removal via acidolysis or catalytic hydrogenation. The compound functions as a versatile building block in synthetic routes to complex heterocycles and pharmaceutical intermediates.

General Information

CAS No. 26275-88-7
Cat. No. CS-0654108
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₂₃NO₂
Molecular Weight 261.36
Synonym(s) None
SMILES CC1(C)CC(OC(C2=CC=CC=C2)=O)CC(C)(C)N1

Computational Chemistry Data

TPSA 38.33
LogP 3.1526
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2,2,6,6-Tetramethylpiperidin-4-yl benzoate

CAS No. 26275-88-7

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