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Structure of 2646-97-1
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3-(Trifluoromethyl)aniline hydrochloride offers a robust, bench-stable platform for constructing electron-deficient aromatic scaffolds. The trifluoromethyl group imparts strong inductive withdrawal and enhanced metabolic stability, while the protonated aniline moiety ensures excellent solubility in aqueous and polar organic media. This salt form facilitates handling and incorporation into synthetic sequences without decomposition.
3-(Trifluoromethyl)aniline hydrochloride serves as a stable, bench-ready building block for the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the aniline functionality enables direct coupling reactions, electrophilic substitution, and amide formation under standard conditions. The hydrochloride salt improves solubility and handling, facilitating purification and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: