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Structure of 27023-19-4
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2,5-Dichloro-3,6-dimethylpyrazine features a rigid pyrazine core substituted with chlorine and methyl groups at strategic positions, delivering enhanced stability and tunable reactivity. This electron-deficient heterocycle serves as a valuable scaffold in synthetic medicinal chemistry, enabling efficient coupling reactions under mild conditions.
2,5-Dichloro-3,6-dimethylpyrazine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling the construction of substituted pyrazine scaffolds via palladium-catalyzed cross-coupling reactions. Its halogenated positions offer high reactivity in Suzuki-Miyaura and Stille couplings, while the methyl groups enhance solubility and metabolic stability. The compound exhibits excellent bench stability and is readily purified by flash chromatography, facilitating integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: