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Ethyl 2-hydroxyimidazo[1,2-a]pyridine-3-carboxylate

  • CAS No. 27124-44-3

  • Cat. No. CS-0151807
  • Molecule weight206.20
  • Purity≥97%
  • MDL No.MFCD26404011

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-hydroxyimidazo[1,2-a]pyridine-3-carboxylate|CS-0151807

Structure of 27124-44-3

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General Information

  • CAS No. 27124-44-3
  • Cat. No. CS-0151807
  • Purity ≥97%
  • MDL No. MFCD26404011
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀N₂O₃
  • Molecular Weight 206.20
  • Synonym(s) 2-Hydroxy-imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
  • SMILES CCOC(=O)C1=C(N=C2C=CC=CN21)O

Description

Ethyl 2-hydroxyimidazo[1,2-a]pyridine-3-carboxylate features a fused heterocyclic core with a pendant hydroxyl and ester group, enabling direct incorporation into synthetic sequences. This bench-stable scaffold delivers high functional group compatibility for medicinal chemistry applications.

Application

Ethyl 2-hydroxyimidazo[1,2-a]pyridine-3-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and synthetic methodology development. The imidazopyridine core enables robust functionalization at multiple positions, while the ethyl ester and hydroxyl groups offer orthogonal reactivity for downstream derivatization. Its bench-stable nature and compatibility with standard coupling and protection strategies facilitate efficient access to complex scaffolds in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.83
  • LogP   1.2166
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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