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Structure of 2713-29-3
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4-Fluoro-2-iodophenol features a fluorine atom at the para position and an iodine substituent at the ortho position relative to the phenolic hydroxyl group. This electronic configuration enhances reactivity in cross-coupling processes while maintaining stability under standard conditions. The compound serves as a key intermediate in the synthesis of functionalized aryl derivatives for pharmaceutical and agrochemical applications.
4-Fluoro-2-iodophenol serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of biaryl scaffolds via palladium-catalyzed reactions. The ortho-iodo group exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the para-fluoro substituent provides additional handle for further functionalization. Its bench-stable solid form and compatibility with diverse reaction conditions make it ideal for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: