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Structure of 27398-39-6
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3-Chloro-2-pyrazine-carboxylic acid features a pyrazine core bearing a chloro substituent at the 3-position and a carboxylic acid group at the 2-position, enabling direct integration into heterocyclic scaffolds. This electron-deficient motif facilitates coupling reactions under mild conditions, offering reliable access to bioactive intermediates in medicinal chemistry.
3-Chloro-2-pyrazine-carboxylic acid serves as a versatile building block in the synthesis of heterocyclic pharmaceutical intermediates. Its dual functionality—pyrazine core and carboxylic acid—enables direct amidation, esterification, or coupling reactions under standard conditions. The chloro substituent facilitates nucleophilic aromatic substitution, allowing access to diverse substituted pyrazine scaffolds. Bench-stable and readily purified by recrystallization, it supports scalable synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: