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Structure of 27825-21-4
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Methyl 3-chloropyrazine-2-carboxylate features a chlorinated pyrazine core that delivers enhanced electrophilicity at the C3 position, enabling efficient coupling reactions in heterocyclic synthesis. This bench-stable, moisture-tolerant reagent integrates readily into medicinal chemistry workflows, serving as a key intermediate for bioactive compound libraries.
Methyl 3-chloropyrazine-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrazine-based pharmacophores. Its chloro group at the C3 position facilitates nucleophilic substitution reactions, while the ester functionality supports subsequent transformations such as hydrolysis or reduction. The compound exhibits good bench stability and is compatible with standard coupling protocols, making it valuable for medicinal chemistry campaigns targeting kinase inhibitors and other bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: