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Structure of 655247-45-3
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Ethyl 3-chloropyrazine-2-carboxylate features a chlorinated pyrazine core enabling direct functionalization in heterocyclic synthesis. This bench-stable, moisture-tolerant reagent integrates readily into cross-coupling and nucleophilic substitution workflows, delivering access to complex nitrogen-rich scaffolds with high regioselectivity.
Ethyl 3-chloropyrazine-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrazine-based scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. The chloro group at the 3-position exhibits high reactivity toward amines, thiols, and organometallic reagents, facilitating rapid diversification. Its bench-stable nature and compatibility with common reaction conditions make it well-suited for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: