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Structure of 27667-34-1
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4-Methoxyquinolin-2(1H)-one features a quinolinone core with a methoxy group at the 4-position, enhancing electron density and solubility. This scaffold integrates readily into medicinal chemistry libraries, offering improved metabolic stability and favorable pharmacokinetic profiles in bioactive molecule design.
4-Methoxyquinolin-2(1H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to quinoline-based bioactive molecules. Its ortho-carbonyl and methoxy functionalities offer predictable reactivity in electrophilic substitution, palladium-catalyzed coupling, and functionalization reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H302-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: