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Structure of 27746-03-8
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4-Chloro-1H-pyrrole-2-carboxylic acid features a chlorinated pyrrole core with a carboxylic acid group at the C2 position, delivering enhanced electron-withdrawing character and improved solubility in polar solvents. This scaffold integrates readily into bioactive molecule design, offering a robust platform for medicinal chemistry and synthetic methodology development under standard conditions.
4-Chloro-1H-pyrrole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via standard coupling reactions. Its carboxylic acid functionality facilitates amide and ester formation under mild conditions, while the chloropyrrole moiety offers enhanced reactivity for subsequent cross-coupling or nucleophilic substitution. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable regiochemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: