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Structure of 277756-45-3
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This trifluoromethyl-substituted cyclobutane carboxylic acid features a rigid, strained ring system that enhances metabolic stability. The electron-withdrawing trifluoromethyl group imparts strong acidity and improved lipophilicity, making it valuable for medicinal chemistry applications. Designed for use in drug discovery, it integrates readily into bioactive scaffolds via standard coupling reactions.
1-(Trifluoromethyl)cyclobutanecarboxylic acid serves as a valuable building block for bioactive molecule synthesis, offering enhanced metabolic stability and lipophilicity due to the electron-withdrawing trifluoromethyl group. Its cyclobutane scaffold provides conformational rigidity, enabling precise spatial orientation in medicinal chemistry applications. The carboxylic acid functionality facilitates direct derivatization or coupling reactions, while the compound exhibits good bench stability and compatibility with standard purification methods.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: