Hydroxy-PEG1-CH2-Boc

Name: Hydroxy-PEG1-CH2-Boc
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 287174-32-7
Cat. No. CS-0115009
Purity≥95%
MDL No.MFCD27635155

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 287174-32-7

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Description

Hydroxy-PEG1-CH2-Boc features a hydroxyl-terminated PEG chain linked to a Boc-protected amine via a methylene spacer. This bifunctional construct enables selective conjugation and protection strategies in peptide synthesis and bioconjugation workflows. The hydrophilic PEG segment enhances solubility, while the stable Boc group facilitates controlled deprotection under mild acidic conditions.

Application

Hydroxy-PEG1-CH2-Boc serves as a versatile, bench-stable building block for the synthesis of PEGylated compounds and bioconjugates. The hydroxyl group enables straightforward derivatization, while the Boc-protected amine offers orthogonal functionality for sequential coupling strategies. Its PEG1 spacer provides enhanced solubility and reduced aggregation in aqueous environments, facilitating purification and downstream applications in drug delivery and peptide chemistry.

General Information

CAS No. 287174-32-7
Cat. No. CS-0115009
Purity ≥95%
MDL No. MFCD27635155
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₆O₄
Molecular Weight 176.21
Synonym(s) None
SMILES O=C(OC(C)(C)C)COCCO

Computational Chemistry Data

TPSA 55.76
LogP 0.337
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Skeleton Fatty chain compounds

Life Science Linker Hydroxy PEG

Life Science PROTAC PROTAC Linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Hydroxy-PEG1-CH2-Boc

CAS No. 287174-32-7

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