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CS-W001157 4
Total: USD 88.00

3-(2-Bromoethyl)-3-methyl-3H-diazirine

  • CAS No. 29205-50-3

  • Cat. No. CS-0197123
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(2-Bromoethyl)-3-methyl-3H-diazirine|CS-0197123

Structure of 29205-50-3

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General Information

  • CAS No. 29205-50-3
  • Cat. No. CS-0197123
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BrN₂
  • Molecular Weight 163.02
  • Synonym(s) None
  • SMILES CC1(CCBr)N=N1

Description

3-(2-Bromoethyl)-3-methyl-3H-diazirine is a photoactivatable crosslinker featuring a reactive diazirine ring and a bromoethyl tether. This combination enables site-specific, UV-induced covalent labeling of proximal biomolecules. The molecule demonstrates robust stability under ambient conditions and facilitates efficient conjugation in biological systems.

Application

3-(2-Bromoethyl)-3-methyl-3H-diazirine serves as a versatile photoaffinity labeling reagent, enabling site-specific protein crosslinking upon UV irradiation. The bromoethyl side chain facilitates conjugation via nucleophilic substitution, while the diazirine ring provides high photoreactivity and stability under ambient conditions. This compound functions effectively in biological target identification workflows, offering reliable attachment to amino acid residues with minimal background reactivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H318-H335
Precautionary Statements : P210-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   24.72
  • LogP   1.9534
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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