Fmoc-D-Glu-NH2

Name: Fmoc-D-Glu-NH2
Brand: ChemScene
Availability: InStock
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CAS No. 292150-20-0
Cat. No. CS-0133843
Purity≥96%
MDL No.MFCD01861343

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

Fmoc-D-Glu-NH₂ serves as a key chiral building block in solid-phase peptide synthesis, featuring a protected D-glutamic acid side chain. The Fmoc group enables orthogonal deprotection under mild basic conditions, while the terminal amine supports efficient coupling reactions. This configuration ensures high stability and compatibility with automated synthesis platforms.

Application

Fmoc-D-Glu-NH₂ serves as a key building block in solid-phase peptide synthesis, enabling the incorporation of D-glutamic acid residues with high fidelity. The Fmoc group provides orthogonal protection for the α-amino function, allowing selective deprotection under mild basic conditions. Its side-chain carboxylate is readily activated for coupling or modified via standard esterification, facilitating diverse conjugation strategies. The compound exhibits excellent bench stability and compatibility with common purification methods, making it ideal for synthesizing bioactive peptides and peptidomimetics.

General Information

CAS No. 292150-20-0
Cat. No. CS-0133843
Purity ≥96%
MDL No. MFCD01861343
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₂₀N₂O₅
Molecular Weight 368.38
Synonym(s) Fmoc-D-isoGln-OH
SMILES O=C(O)CC[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(N)=O

Computational Chemistry Data

TPSA 118.72
LogP 2.2438
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Fmoc

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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Fmoc-D-Glu-NH2

CAS No. 292150-20-0

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