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CS-W001157 4
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1H-Imidazo[4,5-b]pyridine-2(3H)-thione

  • CAS No. 29448-81-5

  • Cat. No. CS-0043982
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1H-Imidazo[4,5-b]pyridine-2(3H)-thione|CS-0043982

Structure of 29448-81-5

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Description

1H-Imidazo[4,5-b]pyridine-2(3H)-thione features a fused heterocyclic core with a thione functionality that enables robust coordination in metal-ligand systems. This bench-stable scaffold integrates readily into bioactive molecule design, offering enhanced solubility and electronic tuning for applications in medicinal chemistry and materials science.

Application

1H-Imidazo[4,5-b]pyridine-2(3H)-thione serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused imidazopyridine-thione core enables robust functionalization at multiple positions, facilitates transition metal-catalyzed coupling reactions, and exhibits favorable stability under standard synthetic conditions. The thione functionality enhances reactivity in nucleophilic substitution and coordination chemistry, supporting efficient access to complex scaffolds and potential ligand design.

General Information

  • CAS No. 29448-81-5
  • Cat. No. CS-0043982
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅N₃S
  • Molecular Weight 151.19
  • Synonym(s) 3H-Imidazo[4,5-b]pyridine-2-thiol
  • SMILES S=C1NC2=NC=CC=C2N1

Computational Chemistry Data

  • TPSA   44.47
  • LogP   1.62049
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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