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Structure of 29682-39-1
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1-Bromo-2-chloro-4-nitrobenzene features a trifunctional aryl scaffold with distinct electrophilic handles. The bromo and chloro substituents enable sequential cross-coupling, while the para-nitro group provides a polar anchor for derivatization. This electron-deficient system facilitates nucleophilic aromatic substitution under mild conditions.
1-Bromo-2-chloro-4-nitrobenzene serves as a versatile dihalogenated aromatic building block for cross-coupling reactions and nucleophilic substitution processes. Its orthogonal reactivity enables selective functionalization at the bromo or chloro site, facilitating the construction of complex heterocycles and pharmaceutical scaffolds. The nitro group enhances electrophilicity for directed metallation and supports downstream reduction to aniline derivatives. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H332-H311-H315-H319-H335-H373
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: