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Structure of 681128-39-2
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This difluorocyclobutylmethanol features a strained cyclobutane ring bearing two fluorine atoms at adjacent positions, imparting enhanced metabolic stability and lipophilic character. The primary alcohol functionality enables direct derivatization or incorporation into bioactive scaffolds. Designed for synthetic applications in medicinal chemistry and agrochemical development.
(3,3-Difluorocyclobutyl)methanol serves as a valuable building block for fluorinated heterocycles and bioactive molecule synthesis. Its difluorocyclobutane core imparts metabolic stability and enhanced membrane permeability, while the primary alcohol facilitates straightforward derivatization via esterification, ether formation, or coupling reactions. The compound exhibits good bench stability and functional group tolerance, enabling efficient incorporation into complex scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1987
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501
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Lot numbers can be found on the outside label of a product: