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Structure of 3044-06-2
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Diethyl 2-(1-ethoxyethylidene)malonate is a bench-stable, moisture-tolerant diester that integrates a reactive ethoxy-substituted alkene. This structure enables efficient Michael addition and conjugate addition protocols in synthetic workflows. The electron-deficient double bond facilitates nucleophilic capture under mild conditions, delivering functionalized malonate derivatives with high regiocontrol.
Diethyl 2-(1-ethoxyethylidene)malonate serves as a versatile diester building block for heterocyclic synthesis, enabling efficient access to substituted pyrroles and other nitrogen-containing scaffolds via multicomponent reactions. Its α,β-unsaturated enol ether functionality facilitates conjugate additions and cycloadditions under mild conditions, while the ethoxy substituent enhances bench stability and simplifies purification. Functions reliably in standard synthetic workflows requiring controlled electrophilic reactivity and orthogonal functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: