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CS-W001157 4
Total: USD 88.00

Ethyl 2-(ethoxymethylene)-3-oxobutyrate

  • CAS No. 3788-94-1

  • Cat. No. CS-M2053
  • Purity≥95%
  • MDL No.MFCD06797311
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(ethoxymethylene)-3-oxobutyrate|CS-M2053

Structure of 3788-94-1

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Description

Ethyl 2-(ethoxymethylene)-3-oxobutyrate is a versatile β-keto ester derivative featuring a conjugated enol ether system. This structure enables efficient Michael additions and Claisen condensations under mild conditions, delivering complex carbonyl architectures with high regiocontrol. The ethoxymethylene group enhances reactivity while maintaining bench-stable handling characteristics.

Application

Ethyl 2-(ethoxymethylene)-3-oxobutyrate serves as a versatile β-keto ester building block in synthetic organic chemistry, enabling efficient construction of substituted pyran and furan heterocycles. Its well-defined reactivity facilitates aldol-type condensations and Michael additions, while the ethoxymethylene group supports facile functionalization via Knoevenagel or Claisen-type reactions. Bench-stable and amenable to straightforward purification, it functions reliably in multi-step syntheses requiring controlled carbon-carbon bond formation.

General Information

  • CAS No. 3788-94-1
  • Cat. No. CS-M2053
  • Purity ≥95%
  • MDL No. MFCD06797311
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄O₄
  • Molecular Weight 186.21
  • Synonym(s) Acetoacetic acid, 2-(ethoxymethylene)-, ethyl ester; ethyl 2-(ethoxymethylidene)-3-oxobutanoate
  • SMILES CC(/C(C(OCC)=O)=C\OCC)=O

Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.0589
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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