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CS-W001157 4
Total: USD 88.00

tert-​Butyl (2R,​5S)​-​2,​5-​dimethylpiperazine-​1-​carboxylate

  • CAS No. 309915-46-6

  • Cat. No. CS-B0967
  • Purity≥98%
  • MDL No.MFCD06797728
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-​Butyl (2R,​5S)​-​2,​5-​dimethylpiperazine-​1-​carboxylate|CS-B0967

Structure of 309915-46-6

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Description

tert-Butyl (2R,5S)-2,5-dimethylpiperazine-1-carboxylate features a stereochemically defined piperazine core with two methyl substituents at the 2- and 5-positions, delivering enhanced conformational rigidity. The tert-butyl ester group provides excellent stability and ease of handling under standard conditions, enabling straightforward deprotection to yield the parent amine for downstream applications in medicinal chemistry and catalyst design.

Application

tert-Butyl (2R,5S)-2,5-dimethylpiperazine-1-carboxylate serves as a stereochemically defined piperazine building block, enabling the efficient construction of complex heterocyclic scaffolds in medicinal chemistry. Its tert-butyl carbamate group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. The defined (2R,5S) stereochemistry ensures predictable conformational behavior in downstream applications, while the dimethyl substitution enhances metabolic stability and modulates solubility in synthetic workflows.

General Information

  • CAS No. 309915-46-6
  • Cat. No. CS-B0967
  • Purity ≥98%
  • MDL No. MFCD06797728
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂N₂O₂
  • Molecular Weight None
  • Synonym(s) TERT-BUTYL(2R,5S)-2,5-DIMETHYLPIPERAZINE-1-CARBOXYLATE
  • SMILES O=C(N1[C@H](C)CN[C@@H](C)C1)OC(C)(C)C

Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.6037
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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