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Structure of 31224-82-5
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5-(Trifluoromethyl)pyridine-2-carboxaldehyde features a trifluoromethyl group at the 5-position and an aldehyde functional group at the 2-position of a pyridine ring. This electron-deficient heteroaromatic scaffold enables efficient coupling in cross-coupling and condensation reactions, offering enhanced stability and solubility in polar organic solvents.
5-(Trifluoromethyl)pyridine-2-carboxaldehyde serves as a versatile building block in medicinal chemistry and catalyst design, enabling efficient construction of heterocyclic scaffolds via nucleophilic addition and condensation reactions. The aldehyde functionality offers high reactivity in imine formation and Mannich-type processes, while the trifluoromethyl group enhances metabolic stability and modulates electronic properties. Bench-stable and compatible with common functional groups, it facilitates streamlined synthesis of bioactive molecules and advanced ligands.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: