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Structure of 312300-42-8
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6-Methoxypyridine-3-sulfonyl chloride is a bench-stable, moisture-tolerant sulfonyl chloride reagent featuring a pyridine scaffold with orthogonal functional handles. The methoxy group enhances solubility in polar organic solvents, while the sulfonyl chloride moiety enables efficient coupling to amines and thiols under mild conditions. This reagent streamlines the synthesis of sulfonamide and thioether derivatives in medicinal chemistry workflows.
6-Methoxypyridine-3-sulfonyl chloride serves as a versatile sulfonylating agent for the synthesis of sulfonamide derivatives. Its reactivity enables efficient coupling with amines under mild conditions, offering high functional group tolerance and straightforward purification. The methoxy-substituted pyridine scaffold enhances solubility and stability, making it well-suited for medicinal chemistry applications and scale-up in API intermediate development.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: