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Structure of 31599-61-8
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4-Iodo-1,2-dimethylbenzene features a sterically hindered aryl iodide scaffold with methyl groups at ortho positions, enhancing stability and directing regioselective cross-coupling. This bench-stable reagent integrates efficiently into palladium-catalyzed transformations, enabling precise construction of complex substituted arenes under standard conditions.
4-Iodo-1,2-dimethylbenzene serves as a versatile aryl iodide building block for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The ortho-methyl groups provide steric and electronic modulation, enhancing regioselectivity in subsequent transformations. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis of complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: