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Structure of 31686-93-8
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Methyl 2-amino-6-methylnicotinate is a bench-stable, electron-rich heterocyclic ester featuring a para-substituted pyridine core. This compound integrates a methyl ester group and an amino functionality at adjacent ring positions, enabling direct coupling in late-stage functionalization. The methyl substituent enhances lipophilicity and metabolic stability, making it suitable for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
Methyl 2-amino-6-methylnicotinate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds relevant to medicinal chemistry. The ortho-amino and ester functionalities offer complementary reactivity for sequential functionalization, while the methyl group enhances metabolic stability. Bench-stable and readily purified by column chromatography, it facilitates scalable transformations including cyclizations, coupling reactions, and derivatization protocols commonly employed in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: