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CS-W001157 4
Total: USD 88.00

5-Amino-2-chlorobenzotrifluoride

  • CAS No. 320-51-4

  • Cat. No. CS-W019997
  • Purity≥98%
  • MDL No.MFCD00007846

*For research and further manufacturing use only, not for direct human use.

5-Amino-2-chlorobenzotrifluoride|CS-W019997

Structure of 320-51-4

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General Information

  • CAS No. 320-51-4
  • Cat. No. CS-W019997
  • Purity ≥98%
  • MDL No. MFCD00007846
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClF₃N
  • Molecular Weight 195.57
  • Synonym(s) None
  • SMILES ClC1=C(C(F)(F)F)C=C(N)C=C1

Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Application

5-Amino-2-chlorobenzotrifluoride serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-chloro and amino groups provide complementary reactivity for palladium-catalyzed cross-coupling and electrophilic substitution, while the trifluoromethyl group enhances metabolic stability and lipophilicity. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of complex intermediates in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.941
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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