(R)-1-(3,4-Difluorophenyl)ethanamine

Name: (R)-1-(3,4-Difluorophenyl)ethanamine
Brand: ChemScene
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CAS No. 321318-15-4
Cat. No. CS-0000317
Purity≥98%
MDL No.MFCD06761760

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(3,4-Difluorophenyl)ethanamine|CS-0000317

Structure of 321318-15-4

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Description

(R)-1-(3,4-Difluorophenyl)ethanamine is a chiral amine featuring a sterically hindered ethylamine moiety attached to a fluorinated aromatic ring. This bench-stable, moisture-tolerant compound integrates readily into asymmetric synthesis workflows, serving as a key scaffold for pharmaceutical intermediates and catalysts.

Application

(R)-1-(3,4-Difluorophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of enantioselective pharmaceutical intermediates. Its bench-stable nature and compatibility with standard amine transformations facilitate efficient access to diverse β-amino carbonyl compounds and heterocyclic scaffolds relevant to drug discovery.

General Information

CAS No. 321318-15-4
Cat. No. CS-0000317
Purity ≥98%
MDL No. MFCD06761760
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉F₂N
Molecular Weight 157.16
Synonym(s) Benzenemethanamine, 3,4-difluoro-alpha-methyl-, (alphaR)- (9CI)
SMILES FC1=C(F)C=CC([C@@H](C)N)=C1

Computational Chemistry Data

TPSA 26.02
LogP 1.9845
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(3,4-Difluorophenyl)ethanamine

CAS No. 321318-15-4

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