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CS-W001157 4
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Methyl (1R,3R,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate

  • CAS No. 321744-17-6

  • Cat. No. CS-0470973
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (1R,3R,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate|CS-0470973

Structure of 321744-17-6

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General Information

  • CAS No. 321744-17-6
  • Cat. No. CS-0470973
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) (1R,2S,4R)-N-Boc-1-amino-2-hydroxycyclopentane-4-carboxylic acid methyl ester
  • SMILES COC(=O)[C@@H]1C[C@@H](NC(=O)OC(C)(C)C)[C@@H](O)C1

Synthesis

  • Route1
    • Methyl (3S,4R)-4-((tert-butoxycarbonyl)amino)-3-hydroxycyclopent-1-ene-1-carboxylate|CS-0494386
      329910-42-1
    • ~99%
    • Methyl (1R,3R,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate|CS-0470973
      321744-17-6

    References

    • Lloyd, Richard C.; Lloyd, Michael C.; Smith, Mark E. B.; Holt, Karen E.; Swift, Jonathan P.; Keene, Philip A.; Taylor, Stephen J. C.; McCague, Raymond Tetrahedron, 2004 , vol. 60, # 3 p. 717 - 728
  • Route2

    References

    • Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705
  • Route3

    References

    • Smith, Mark E.B.; Derrien, Nadine; Lloyd, Michael C.; Taylor, Stephen J.C.; Chaplin, David A.; McCague, Raymond Tetrahedron Letters, 2001 , vol. 42, # 7 p. 1347 - 1350

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   0.8236
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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