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CS-W001157 4
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Methyl (1S,3R,4S)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclopentane-1-carboxylate

  • CAS No. 321744-14-3

  • Cat. No. CS-0049303
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (1S,3R,4S)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclopentane-1-carboxylate|CS-0049303

Structure of 321744-14-3

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General Information

  • CAS No. 321744-14-3
  • Cat. No. CS-0049303
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) Boc-Gly-OH-2-13C
  • SMILES COC(=O)[C@@H]1C[C@H](O)[C@@H](C1)NC(=O)OC(C)(C)C

Synthesis

  • Route1
    • Methyl (3S,4R)-4-((tert-butoxycarbonyl)amino)-3-hydroxycyclopent-1-ene-1-carboxylate|CS-0494386
      329910-42-1
    • ~%
    • Methyl (1S,3R,4S)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclopentane-1-carboxylate|CS-0049303
      321744-14-3

    References

    • US6593489 B1, ;
  • Route2
    • null|null
      79-22-1
    • (1S,3R,4S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxycyclopentanecarboxylic acid|CS-1230394
      952708-31-5
    • ~93%
    • Methyl (1S,3R,4S)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclopentane-1-carboxylate|CS-0049303
      321744-14-3

    References

    • Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705
  • Route3

    References

    • Tetrahedron, , vol. 60, # 3 p. 717 - 728

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   0.8236
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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