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CS-W001157 4
Total: USD 88.00

Methyl (1S,3S,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate

  • CAS No. 321744-19-8

  • Cat. No. CS-0470971
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (1S,3S,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate|CS-0470971

Structure of 321744-19-8

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General Information

  • CAS No. 321744-19-8
  • Cat. No. CS-0470971
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) methyl (1S,3S,4S)-3-hydroxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopentane-1-carboxylate
  • SMILES COC(=O)[C@H]1C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C1

Synthesis

  • Route1
    • Methyl (1R,4S)-4-(tert-Butoxycarbonylamino)cyclopent-2-ene-1-carboxylate|CS-0184613
      251326-99-5
    • ~%
    • Methyl (1S,3S,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate|CS-0470971
      321744-19-8

    References

    • Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705
  • Route2
    • Methyl (3R,4S)-4-((tert-butoxycarbonyl)amino)-3-hydroxycyclopent-1-ene-1-carboxylate|CS-0494385
      329910-37-4
    • ~%
    • Methyl (1S,3S,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate|CS-0470971
      321744-19-8

    References

    • Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705
  • Route3
    • (3R,4S)-4-((tert-Butoxycarbonyl)amino)-3-hydroxycyclopent-1-enecarboxylic acid|CS-0928375
      329910-36-3
    • ~%
    • Methyl (1S,3S,4S)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclopentane-1-carboxylate|CS-0470971
      321744-19-8

    References

    • Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   0.8236
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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