4-Hydroxyphenyl acetate

Name: 4-Hydroxyphenyl acetate
Brand: ChemScene
Availability: InStock
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CAS No. 3233-32-7
Cat. No. CS-B0170
Purity≥98%
MDL No.MFCD00799234

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 3233-32-7

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Description

4-Hydroxyphenyl acetate is a phenolic ester featuring a hydroxyl group at the para position relative to the acetate moiety. This arrangement imparts enhanced stability and solubility in organic solvents, facilitating its use in synthetic transformations requiring controlled release of phenolic components. The compound serves as a protected derivative in pharmaceutical intermediates and bioconjugation workflows.

Application

4-Hydroxyphenyl acetate serves as a stable, bench-ready phenolic protecting group derivative that facilitates selective acetylation and orthogonal deprotection in complex molecule synthesis. It enables reliable handling of phenolic functionalities during multi-step sequences, particularly in carbohydrate and natural product derivatization, where its clean hydrolysis under mild basic conditions supports high-yield transformations without epimerization or side reactions.

General Information

CAS No. 3233-32-7
Cat. No. CS-B0170
Purity ≥98%
MDL No. MFCD00799234
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈O₃
Molecular Weight 152.15
Synonym(s) 4-HPA; 4-Acetoxyphenol
SMILES O=C(C)OC(C=C1)=CC=C1O

Computational Chemistry Data

TPSA 46.53
LogP 1.3175
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Natural Products

Building Blocks Functional Group Phenol

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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4-Hydroxyphenyl acetate

CAS No. 3233-32-7

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