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Structure of 3289-47-2
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2-O-Methylcytosine offers site-specific nucleobase modification with enhanced stability and resistance to enzymatic degradation. This analog integrates seamlessly into oligonucleotide synthesis, providing improved nuclease resilience while maintaining base-pairing fidelity in duplex DNA structures.
2-O-Methylcytosine serves as a valuable nucleoside analog for probing RNA structure and function, offering enhanced metabolic stability compared to unmodified cytosine. It functions as a direct replacement in oligonucleotide synthesis, enabling site-specific incorporation into DNA/RNA strands with minimal perturbation to duplex stability. The methyl ether group confers resistance to enzymatic degradation while maintaining base-pairing fidelity, making it particularly useful in antisense technologies and synthetic biology applications requiring prolonged functional activity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: