4-Bromopyridine-2,6-diamine

Name: 4-Bromopyridine-2,6-diamine
Brand: ChemScene
Availability: InStock
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CAS No. 329974-09-6
Cat. No. CS-0059208
Purity≥97%
MDL No.MFCD04115308

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 329974-09-6

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Description

4-Bromopyridine-2,6-diamine features two amino groups flanking a brominated pyridine core, enabling straightforward functionalization in cross-coupling and cyclization reactions. The electron-rich aromatic system enhances reactivity in transition-metal catalyzed transformations, while the bromine serves as a robust handle for further derivatization. This scaffold delivers high stability under standard conditions and facilitates rapid access to complex heterocyclic architectures in medicinal chemistry and materials science.

Application

4-Bromopyridine-2,6-diamine serves as a versatile building block in medicinal chemistry and materials science, enabling direct access to functionalized pyridine scaffolds. Its two ortho-amino groups facilitate sequential coupling reactions, while the bromine substituent supports palladium-catalyzed cross-coupling transformations. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthesis workflows targeting heterocyclic APIs and advanced ligands.

General Information

CAS No. 329974-09-6
Cat. No. CS-0059208
Purity ≥97%
MDL No. MFCD04115308
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₆BrN₃
Molecular Weight 188.03
Synonym(s) 4-Bromo-2,6-diaminopyridine
SMILES NC1=NC(N)=CC(Br)=C1

Computational Chemistry Data

TPSA 64.93
LogP 1.0085
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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4-Bromopyridine-2,6-diamine

CAS No. 329974-09-6

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