2-Amino-4-bromopyridine

Name: 2-Amino-4-bromopyridine
Brand: ChemScene
Availability: InStock
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CAS No. 84249-14-9
Cat. No. CS-D0698
Purity≥96%
MDL No.MFCD01646115

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 84249-14-9

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Description

2-Amino-4-bromopyridine features a bromine substituent at the 4-position and an amino group at the 2-position, creating a uniquely activated pyridine scaffold. This electronic configuration enables direct coupling reactions with palladium catalysts under standard conditions. The compound serves as a key building block in medicinal chemistry for synthesizing kinase inhibitors and bioactive heterocycles.

Application

2-Amino-4-bromopyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity profile. The amino group facilitates direct functionalization or protection strategies, while the bromine atom provides a reliable handle for C–C bond formation under standard Suzuki, Stille, or Negishi conditions. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for modular heterocycle construction and API intermediate development.

General Information

CAS No. 84249-14-9
Cat. No. CS-D0698
Purity ≥96%
MDL No. MFCD01646115
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅BrN₂
Molecular Weight 173.01
Synonym(s) 4-Bromopyridine-2-amine
SMILES BrC1=CC(N)=NC=C1

Computational Chemistry Data

TPSA 38.91
LogP 1.4263
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H317-H319-H335-H412
Precautionary Statements : P271-P280-P261-P302+P352-P305+P351+P338-P333+P313-P405-P403+P233-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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2-Amino-4-bromopyridine

CAS No. 84249-14-9

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