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CS-W001157 4
Total: USD 88.00

2,5-Dibromo-4-methylpyridine

  • CAS No. 3430-26-0

  • Cat. No. CS-W010214
  • Purity≥97%
  • MDL No.MFCD00234955

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromo-4-methylpyridine|CS-W010214

Structure of 3430-26-0

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General Information

  • CAS No. 3430-26-0
  • Cat. No. CS-W010214
  • Purity ≥97%
  • MDL No. MFCD00234955
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅Br₂N
  • Molecular Weight 250.92
  • Synonym(s) None
  • SMILES CC1=CC(Br)=NC=C1Br

Description

2,5-Dibromo-4-methylpyridine features a pyridine core bearing two bromine atoms at the 2- and 5-positions and a methyl group at the 4-position. This electron-deficient heterocycle serves as a key building block for C–C and C–heteroatom coupling reactions, offering enhanced reactivity in palladium-catalyzed transformations. The steric profile and halogen positioning enable selective functionalization in complex molecular architectures.

Application

2,5-Dibromo-4-methylpyridine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The methyl group enhances regioselectivity in electrophilic substitution, while the dibromo substitution pattern facilitates sequential functionalization. Its bench stability and compatibility with standard coupling protocols make it a practical choice for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.91502
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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