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Structure of 34321-81-8
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Mal-PEG2-alcohol features a maleimide group conjugated to a short, hydrophilic PEG2 spacer terminating in a primary alcohol. This structure enables site-specific bioconjugation via thiol-Michael addition, while the terminal OH group supports further derivatization or immobilization. The PEG2 linker enhances solubility and reduces aggregation, making it suitable for protein labeling and probe synthesis under physiological conditions.
Mal-PEG2-alcohol serves as a versatile bifunctional linker for conjugation and polymer synthesis. The maleimide group enables efficient, selective Michael addition with thiols under physiological conditions, while the terminal primary alcohol facilitates further derivatization via esterification or etherification. Its short PEG spacer provides enhanced solubility and reduced steric hindrance, making it ideal for bioconjugation applications requiring precise spacing and stability.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: