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CS-W001157 4
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(2R)-3-Amino-2-fluoropropan-1-ol

  • CAS No. 344413-79-2

  • Cat. No. CS-0053486
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2R)-3-Amino-2-fluoropropan-1-ol|CS-0053486

Structure of 344413-79-2

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General Information

  • CAS No. 344413-79-2
  • Cat. No. CS-0053486
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₈FNO
  • Molecular Weight 93.10
  • Synonym(s) (S)-3-AMINO-2-FLUOROPROPAN-1-OL HCL
  • SMILES NC[C@@H](F)CO

Description

(2R)-3-Amino-2-fluoropropan-1-ol is a chiral fluorinated amino alcohol featuring a stereodefined (2R) configuration. This bench-stable derivative integrates a primary hydroxyl group and a primary amine, enabling efficient coupling and functionalization in synthetic sequences. The fluorine atom imparts enhanced metabolic stability and modulates electronic properties, making it valuable for bioactive molecule synthesis.

Application

(2R)-3-Amino-2-fluoropropan-1-ol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated amino alcohols with defined stereochemistry. Its stability under standard reaction conditions and compatibility with common functional groups facilitate straightforward incorporation into complex molecular architectures. The molecule functions effectively in nucleophilic substitution and coupling reactions, offering reliable access to bioactive scaffolds relevant to CNS-targeted therapeutics and kinase inhibitors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   -0.7245
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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