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CS-W001157 4
Total: USD 88.00

1,4-Dibromo-2-nitrobenzene

  • CAS No. 3460-18-2

  • Cat. No. CS-W002018
  • Purity≥98%
  • MDL No.MFCD00007046
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,4-Dibromo-2-nitrobenzene|CS-W002018

Structure of 3460-18-2

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Description

1,4-Dibromo-2-nitrobenzene features a para-dibrominated aromatic core with a strategically positioned nitro group, delivering enhanced electrophilic reactivity and stability under standard conditions. This electron-deficient scaffold enables efficient coupling in transition-metal-catalyzed transformations, serving as a key building block for advanced heterocyclic systems and functionalized arenes in synthetic organic chemistry.

Application

1,4-Dibromo-2-nitrobenzene serves as a versatile building block in cross-coupling chemistry and heterocycle synthesis. The bromine atoms enable palladium-catalyzed coupling reactions, while the nitro group facilitates subsequent reductions and electrophilic substitutions. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.

General Information

  • CAS No. 3460-18-2
  • Cat. No. CS-W002018
  • Purity ≥98%
  • MDL No. MFCD00007046
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Br₂NO₂
  • Molecular Weight 280.90
  • Synonym(s) Dibro monitrobenzene; 1,4-Dibromo-2-nitrobenzene
  • SMILES Brc1ccc(c(c1)[N+](=O)[O-])Br

Computational Chemistry Data

  • TPSA   43.14
  • LogP   3.1198
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335-H410
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501

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