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Structure of 347146-12-7
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5-Bromoquinolin-2-amine features a bromine atom at the 5-position and an amino group at the 2-position of the quinoline scaffold, enabling selective coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity in palladium-catalyzed transformations under standard conditions.
5-Bromoquinolin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl scaffolds. Its bromine substituent facilitates efficient C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the pendant amine supports derivatization and coordination in catalytic systems. The molecule exhibits good bench stability and is compatible with diverse functional groups, making it a practical choice for the synthesis of quinoline-based pharmaceutical candidates and ligands.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: