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Structure of 35944-64-0
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3-Iodo-4-methylaniline features a para-methyl-substituted aniline scaffold with a reactive iodine handle, enabling direct functionalization in cross-coupling processes. This bench-stable, moisture-tolerant aryl iodide integrates efficiently into complex molecular architectures under standard conditions.
3-Iodo-4-methylaniline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings. The iodine handle provides high reactivity under standard conditions, while the aniline functionality offers moderate basicity and compatibility with common protecting groups. Bench-stable and readily purified by recrystallization, it facilitates efficient access to substituted biaryls and heterocyclic scaffolds relevant to API development.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H317-H318
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: