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Structure of 359878-47-0
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4-(4-Fluorobenzylamino)-1-methylpiperidine features a fluorinated aromatic linker that enhances metabolic stability and membrane permeability. The piperidine core provides a basic nitrogen for salt formation and pharmacophore integration, while the methyl group at the 1-position modulates electronic properties and steric profile. This scaffold is well-suited for medicinal chemistry campaigns targeting CNS receptors and kinase pathways.
4-(4-Fluorobenzylamino)-1-methylpiperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine coupling and functional group interconversions. Its fluorinated aryl moiety enhances metabolic stability and membrane permeability, while the piperidine core provides a basic nitrogen for salt formation and target engagement. The compound exhibits excellent bench stability, ease of purification, and compatibility with common reaction conditions, facilitating integration into multi-step syntheses of CNS-targeted therapeutics and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: