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ETHYL 1-(AMINOMETHYL)CYCLOPROPANECARBOXYLATE HCL

  • CAS No. 362703-20-6

  • Cat. No. CS-0037152
  • Molecule weight179.65
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

ETHYL 1-(AMINOMETHYL)CYCLOPROPANECARBOXYLATE HCL|CS-0037152

Structure of 362703-20-6

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General Information

  • CAS No. 362703-20-6
  • Cat. No. CS-0037152
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.65
  • Synonym(s) Ethyl 1-(Aminomethyl)cyclopropanecarboxylate Hydrochloride
  • SMILES CCOC(=O)C1(CC1)CN.Cl

Description

Ethyl 1-(aminomethyl)cyclopropane-1-carboxylate hydrochloride delivers a rigid cyclopropyl scaffold bearing a pendant aminomethyl group, enabling precise incorporation into bioactive molecules. This bench-stable derivative supports efficient peptide and heterocyclic synthesis under standard conditions.

Application

Ethyl 1-(aminomethyl)cyclopropane-1-carboxylate hydrochloride serves as a versatile building block in medicinal chemistry, enabling the efficient construction of cyclopropyl-containing scaffolds. The amine functionality facilitates direct derivatization via alkylation, acylation, or reductive amination, while the ester group supports subsequent hydrolysis or coupling reactions. Its crystalline solid form ensures bench stability and ease of handling, with excellent functional group tolerance under standard synthetic conditions.

Synthesis

  • Route1

    References

    • Duan, Jingwu; King, Bryan W.; Decicco, Carl; Maduskuie JR., Thomas P.; Voss, Mathew E. Patent: US2004/72802 A1, 2004 ; Location in patent: Page/Page column 45-46 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.7102
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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