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Structure of 363-47-3
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3,5-Difluoro-4-methoxyaniline features a fluorinated aromatic core with complementary electron-donating and withdrawing substituents. This arrangement enhances solubility in polar organic media while maintaining stability under standard bench conditions. The molecule integrates readily into pharmaceutical intermediates and functional materials, offering precise tuning of electronic properties through its orthogonal substitution pattern.
3,5-Difluoro-4-methoxyaniline serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds through standard coupling reactions. Its ortho-fluoro substituents facilitate subsequent C–H functionalization, while the methoxy group offers moderate electron-donating character and enhanced solubility. The compound exhibits good bench stability and is compatible with common protecting group strategies, facilitating downstream transformations in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: