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CS-W001157 4
Total: USD 88.00

2,3-Dichloro-1-fluoro-4-nitrobenzene

  • CAS No. 36556-51-1

  • Cat. No. CS-W005862
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Dichloro-1-fluoro-4-nitrobenzene|CS-W005862

Structure of 36556-51-1

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General Information

  • CAS No. 36556-51-1
  • Cat. No. CS-W005862
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₂FNO₂
  • Molecular Weight 209.99
  • Synonym(s) 2,3-Dichloro-4-fluoronitrobenzene
  • SMILES FC1=CC=C([N+]([O-])=O)C(Cl)=C1Cl

Description

2,3-Dichloro-1-fluoro-4-nitrobenzene features a highly electron-deficient aromatic core with orthogonal halogen and nitro substituents, enabling selective coupling reactions in synthetic organic chemistry. This bench-stable reagent integrates efficiently into multi-step syntheses requiring precise regiocontrol and enhanced electrophilicity.

Application

2,3-Dichloro-1-fluoro-4-nitrobenzene serves as a versatile electrophilic building block in aromatic substitution reactions, enabling the synthesis of complex heterocyclic scaffolds and functionalized arenes. The fluorine atom facilitates nucleophilic aromatic substitution under mild conditions, while the nitro group enhances reactivity and directs regioselective coupling. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses requiring orthogonal functional group handling.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.14
  • LogP   3.0407
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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