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Structure of 82671-06-5
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2,6-Dichloro-5-fluoronicotinic acid features a trifunctional heteroaryl scaffold with strategically positioned halogens enabling direct coupling in late-stage functionalization. The electron-deficient pyridine core facilitates nucleophilic substitution under mild conditions, while the carboxylic acid group provides a handle for amide formation and conjugation. This compound serves as a key building block in the synthesis of bioactive small molecules and pharmaceutical intermediates.
2,6-Dichloro-5-fluoronicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its orthogonal halogenation pattern facilitates selective cross-coupling reactions, while the carboxylic acid group supports direct derivatization or amide formation. The compound exhibits good bench stability and compatibility with standard reaction conditions, making it suitable for scalable synthesis of pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: