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Structure of 367-78-2
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2-Fluoro-4,6-dinitrobenzenamine features a fluorine atom at the ortho position relative to the amino group, combined with two nitro groups in electron-deficient positions. This configuration enhances electrophilic reactivity while maintaining bench-stable handling characteristics. The compound integrates readily into conjugated systems and serves as a strategic intermediate for nitrogen-rich heterocycles and functionalized aryl scaffolds in synthetic organic chemistry.
2-Fluoro-4,6-dinitrobenzenamine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its electron-deficient aromatic core enables efficient nucleophilic substitution reactions, facilitating the construction of complex scaffolds. The fluorine and dinitro groups provide orthogonal reactivity and enhanced solubility, while the amine functionality allows for direct derivatization. This compound exhibits bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331-H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: