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Structure of 367-83-9
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2-Fluoro-5-methoxybenzoic acid features a strategically positioned fluorine atom and methoxy group on the aromatic ring, enabling enhanced metabolic stability and tailored electronic properties. This configuration supports efficient incorporation into pharmaceutical intermediates and bioactive scaffolds under standard conditions.
2-Fluoro-5-methoxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functional groups—fluorine, methoxy, and carboxylic acid—facilitate diverse transformations including amide coupling, Suzuki-Miyaura cross-coupling, and electrophilic aromatic substitution. The compound exhibits good bench stability, ease of purification, and compatibility with standard reaction conditions, making it well-suited for iterative synthetic campaigns in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: