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Ethyl 3-aminofuro[2,3-b]pyridine-2-carboxylate

  • CAS No. 371945-06-1

  • Cat. No. CS-0035031
  • Purity≥97%
  • MDL No.MFCD09837639

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-aminofuro[2,3-b]pyridine-2-carboxylate|CS-0035031

Structure of 371945-06-1

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General Information

  • CAS No. 371945-06-1
  • Cat. No. CS-0035031
  • Purity ≥97%
  • MDL No. MFCD09837639
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀N₂O₃
  • Molecular Weight 206.20
  • Synonym(s) Furo[2,3-b]pyridine-2-carboxylic acid, 3-amino-, ethyl ester (9CI)
  • SMILES O=C(C1=C(N)C2=CC=CN=C2O1)OCC

Description

Ethyl 3-aminofuro[2,3-b]pyridine-2-carboxylate features a fused heterocyclic core with a pendant amino group and ester functionality, enabling direct integration into medicinal chemistry campaigns. This bench-stable scaffold supports efficient derivatization and serves as a key intermediate for bioactive nitrogen-containing compounds.

Application

Ethyl 3-aminofuro[2,3-b]pyridine-2-carboxylate serves as a versatile building block for furo[2,3-b]pyridine-based heterocycles, enabling efficient access to pharmaceutically relevant scaffolds. The amino and ester functionalities offer orthogonal reactivity, facilitating downstream derivatization via coupling, alkylation, or cyclization reactions. Bench-stable and readily purified by column chromatography, it functions effectively in multi-step synthesis workflows requiring functional group tolerance and predictable regiochemistry.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.35
  • LogP   1.5867
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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